Webb1 juli 2024 · Our results establish a new paradigm in pancreatic cancer whereby PTHrP is a driver of disease progression and emerges as a novel therapeutic vulnerability. Significance: Pancreatic cancer often presents with metastases, yet no strategies exist to pharmacologically inhibit this process. Webb27 apr. 2015 · POLR2A是一种包括癌细胞在内的细胞生存的必须基因,由于其仅存在单一拷贝,因此癌细胞对于该基因的抑制会异常敏感。 随着POLR2A和TP53基因同时被剔除就 …
PRMT5 Inhibition Drives Therapeutic Vulnerability to BCL-2 …
Webbvulnerable [ 'vʌlnərəbl ] adj. susceptible to attack. "a vulnerable bridge". susceptible to criticism or persuasion or temptation. "vulnerable to bribery"; "an argument vulnerable to … Webb25 feb. 2024 · 印第安纳大学医学院和Simon综合癌症中心的Xiongbin Lu领导的团队早在2015年的Nature上发表题为:TP53 loss creates therapeutic vulnerability in colorectal … chloeshayden
therapeutic是什么意思_therapeutic的翻译_音标_读音_用法_例句_ …
Webbn. 弱点,攻击;易伤性;致命性;脆弱性 英英释义 vulnerability [ ,vʌlnərə'biliti ] n. the state of being vulnerable or exposed "his vulnerability to litigation" 同义词:exposure … Webb18 juni 2024 · Prostate cancer (PCa) is a heterogeneous malignancy and still causes a significant mortality worldwide. 1, 2 Androgen deprivation therapy (ADT) is the main therapeutic regimen for advanced PCa patients. However, most treated patients invariably develop the castration-resistant PCa (CRPC), currently a lethal form of the disease. Webb28 juli 2024 · Colorectal cancer (CRC) is a leading cause of cancer-related deaths globally, with the majority of cases initiated by inactivation of the APC tumor suppressor. This results in the constitutive transcriptional activation of the canonical WNT signal transduction pathway effector β-Catenin, along with induction of WNT feedback … grass valley towing companies