WebApr 11, 2024 · Variable color: skin colored to brown to purple. Variable shape: plaques, nodules or polyps. Covered by intact skin. Suspected by pinching the nodule between the … WebJun 1, 2024 · Epithelioid fibrous histiocytoma (EFH), also known as epithelioid cell histiocytoma (ECH), is an uncommon benign cutaneous mesenchymal neoplasm that typically occurs in the limbs and consistently harbors ALK gene rearrangements. In this study, we report a unique case of EFH that arose in the labia majora, an unusual site …
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WebJul 15, 2024 · Differential diagnosis. Solitary reticulohistiocytoma: younger age, solitary lesions usually not on digits or face ( Am J Surg Pathol 2006;30:521 ) Epithelioid fibrous histiocytoma: usually < 1 cm on extremities, usually no giant cells, primarily myofibroblastic, not histiocytic. Epithelioid sarcoma: deep seated tumor with markedly atypical ... In epithelioid histiocytoma, sections show a centrally located, circumscribed tumour underlying an epidermal collarette (figure 1). The tumour is composed of epithelioid cells arranged in sheets and sometimes a storiform pattern. Individual cells show abundant eosinophilic cytoplasm with round vesicular nuclei and … See more Immunohistochemical studies reveal positivity with Factor 13a, and there is variable positivity with CD68. ALK-1 has been increasingly … See more Melanoma – Amelanotic melanoma will show similar large epithelioid cells but will generally display more pleomorphismand epidermal involvement. S100 positivity is seen in melanoma. … See more billy\u0027s liberty park
Epithelioid histiocytoma pathology DermNet
WebHistiocytosis represents a group of rare disorders characterized by nonneoplastic proliferation of histiocytes and solitary cutaneous reticulohistiocytosis (SCR) is a form of non-Langerhans histiocytosis. SCR consists of small papule, usually single, varying in color from yellow to brownish-red, more frequent in young adults, and uncommon in childhood. … WebReticulohistiocytoma (solitary epithelioid histiocytoma) Solitary epithelioid histiocytoma (SEH) is the newly proposed name for reticulohistiocytoma.38 It is located in the superficial dermis to deep dermis and is composed of large epithelioid histiocytes with lymphocytes and neutrophils. WebEpithelioid fibrous histiocytoma (EFH) is a rare lesion believed to arise from dermal microvascular unit fibroblasts and dendritic histiocytes. EFH has long been considered a … billy\u0027s lawn mower opelousas la