Dynein intermediate chain 2 ciliary
WebFeb 28, 2024 · Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking. Mol Biol Cell 29, 1628–1639. Link, Google Scholar; Harada A, Takei Y, … WebMost of these cases result from mutation in genes encoding dynein-2 components, such as the heavy chain DYNC2H1 gene (Baujat et al., 2013) and the intermediate chain DYNC212 gene (previously known ...
Dynein intermediate chain 2 ciliary
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WebMay 1, 2001 · The dynein heavy chain family of isoforms is divided into four functional classes: (i) axonemal (ciliary or flagellar) outer arm dyneins; (ii) axonemal inner arm dyneins; (iii) non-axonemal (‘cytoplasmic’) ... The orange box denotes a region crucial for dimerization of the heavy chain and binding of the intermediate chain. (b, c ... WebSep 30, 2024 · 37 of dynein motor proteins coordinate their activity to drive ciliary bending wave propagation. Dynein-38 associated light and intermediate chains regulate the biophysical mechanisms of axonemal dynein. Tctex-39 type outer arm dynein light chain 2 (LC2) regulates flagellar bending wave propagation direction,
Each molecule of the dynein motor is a complex protein assembly composed of many smaller polypeptide subunits. Cytoplasmic and axonemal dynein contain some of the same components, but they also contain some unique subunits. Cytoplasmic dynein, which has a molecular mass of about 1.5 megadaltons (MDa), is a dimer of dimers, containing approximately twelve polypeptide sub…
WebMay 1, 2001 · The dynein heavy chain family of isoforms is divided into four functional classes: (i) axonemal (ciliary or flagellar) outer arm dyneins; (ii) axonemal inner arm dyneins; (iii) non-axonemal (‘cytoplasmic’) dynein-1, also called MAP1C, Dhc1a and Dyh1; and (iv) cytoplasmic dynein-2, also called Dhc1b and Dyh2 , . WebDynein intermediate chain 2, ciliary. Status. UniProtKB reviewed (Swiss-Prot) Organism. Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) Amino acids. 702. ...
WebOct 24, 2016 · an effective VHA supply chain management (SCM) program at medical facilities within the Department of Veterans Affairs (VA). 2. SUMMARY OF CONTENT: …
WebTo ensure continuity of service, the facility maintains N+2 generator redundancy. 4Q22 Northern Virginia Data Center Market Report. GET ACCESS. About IAD02 Data Center. … opal shaving brushWebEnter the email address you signed up with and we'll email you a reset link. iowa esports teamsWebDec 28, 2010 · Many individuals with PCD have a mutation in a gene encoding a component of the outer dynein arms (molecular motors that power the 9+2 ciliary cytoskeleton or axoneme), particularly in one of the ... opal sheetsWeb1 day ago · Outer dynein arms in the ciliary axoneme generate force for ciliary beating. Here, cryo-electron tomography study of the outer dynein arm from the unicellular alga … iowa esports arenaWebJun 28, 2024 · The dynein-2 complex mediates trafficking of ciliary proteins by powering the intraflagellar transport (IFT) machinery containing IFT-A and IFT-B complexes. Although 11 subunits are known to constitute the … opal shawWebDec 8, 2024 · Located in 9+2 motile cilium; axoneme; and external side of plasma membrane. Is expressed in spermatozoon and testis. Used to study Kartagener syndrome and primary ciliary dyskinesia. Human ortholog (s) of this gene implicated in primary ciliary dyskinesia 9. Orthologous to human DNAI2 (dynein axonemal intermediate chain 2). … iowa essentialsWebNM_023036.6(DNAI2):c.124G>A (p.Val42Met) AND Primary ciliary dyskinesia 9 Clinical significance: Likely benign (Last evaluated: Jan 13, 2024) Review status: 1 star out of maximum of 4 stars opalshelter.us