Cisplatin hyponatriämie

WebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with ... WebJan 1, 2024 · Hyponatremia in cancer patients can be caused by a number of factors including gastrointestinal losses, cardiac failure, diabetes insipidus, cancer-induced physiological changes or hormonal secretion, pulmonary diseases, central nervous system disorders, several drugs other than anticancer treatments (e.g., chlorpropamide, …

Cisplatin and hypomagnesemia - ScienceDirect

WebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis … WebHyponatremia was defined and graded using the Common Terminology Criteria for Adverse Events, version 4.0, as follows: a serum sodium concentration from lower limit of normal to 130 mEq/L, grade 1; … opening a business nz https://serranosespecial.com

Cisplatin-induced anorexia and ghrelin - PubMed

WebAug 1, 2002 · We report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the patient was treated with a sodium supplement. We also summarize the key diagnostic features and the most common differential diagnoses for hyponatremia syndrome. WebCisplatin-induced hyponatremia and renal sodium wast-ing. Acta Oncol 1995;34:264-5. 12. Cao L, Joshi P, Sumoza D. Renal salt-wasting syndrome in a patient with cisplatin-induced hyponatremia. Am J WebHyponatremia is a rare complication associated with cisplatin. The mechanism by which it causes hyponatremia is thought to be due to either inducing SIADH or by renal salt wasting syndrome (RSWS) [1]. It is unclear why it occurs but it is believed that pharmacogenetics plays an essential role. iowa timber land for sale

Differential diagnosis of hyponatremia induced by …

Category:Electrolyte disorders with platinum-based chemotherapy: …

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Cisplatin hyponatriämie

Differential diagnosis of hyponatremia induced by …

WebApr 27, 2024 · Hyponatremia is a common adverse effect induced by cisplatin. Caution should be exercised with patients with a low sodium level before starting chemotherapy. Hyponatremia can be associated with other chemotherapy-related adverse effects, and it should therefore be treated correctly. Introduction Webmostly solid tumors had hyponatremia, and of these, 11% had moderate (sodium [Na] 120–129 mEq/L) to severe (Na , 120 mEq/L) hyponatremia (1). This is disproportionately higher than the hyponatremia prevalence rates of 15%–30% reported for general medicine admissions (2). In cancer patients with nonsolid tumors, rates of hyponatremia are less.

Cisplatin hyponatriämie

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WebJul 20, 2024 · Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia, hypophosphatemia, Electrolyte disorders with platinum … WebFeb 1, 1999 · Hypomagnesemia is a well known side-effect in patients receiving cisplatin-containing chemotherapy. Cisplatin induces hypomagnesemia through its renal toxicity possibly by a direct injury to mechanisms of magnesium reabsorption in the ascending limb of the loop of Henle as well as the distal tubule.

WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be dose … WebKeywords: Cisplatin, Dehydration, Hyponatremia, Renal salt wasting, Siadh. Case Presentation: A 63-year-old male presents to the hospital with complaints of one-day history of weakness, dizziness. His outpatient blood work demonstrated a serum sodium level of 124 mEq/L, and a creatinine of 3.1 mg/dL. His medical history was significant for high ...

WebNov 1, 1997 · Cisplatin is one of the most widely used agents in cancer treatment. Cisplatin regimens can lead to a more or less pronounced hyponatremia in 4 to 10% of cases due to salt wasting with... WebHyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) or gastrointestinal loss of sodium is sometimes seen during chemotherapy. However, …

WebHyponatremia is one of the common electrolyte disorders associated with cisplatin (CDDP) administration. We report here two cases of hyponatremia associated with CDDP. Case 1 : A 75-year-old man with urothelial carcinoma of bladder (cT3N1M0) underwent neoadjuvant chemotherapy with CDDP and gemcitabi …

WebMay 22, 2012 · The development of hyponatremia during cisplatin therapy bears special mention. Cisplatin stimulates AVP secretion to cause SIADH, but it can also directly damage renal tubules to interfere with sodium … iowa ticketsWebNational Center for Biotechnology Information opening a business with a friendWebdromes have distinct clinical characteristics and managements. The key differential diagnostic feature for RSWS is the excessive urinary excretion of sodium, whereas the urinary excretion of sodium in SIADH is normal or decreased. The treatment for RSWS is supplement of salt, which is opposite to the treatment of SIADH. We report a case of a … opening a business onlineWebJun 11, 2024 · INTRODUCTION Hyponatremia represents a relative excess of water in relation to sodium. It can be induced by a marked increase in water intake (primary polydipsia) and/or by impaired water excretion due, for example, to advanced kidney failure or persistent release of antidiuretic hormone (ADH). (See "Causes of hypotonic … iowa tiger hawkeye clip artWebHyponatremia is a rare complication associated with cisplatin. The mechanism by which it causes hyponatremia is thought to be due to either inducing SIADH or by renal salt … iowa ticks picturesWebJul 7, 2024 · 1 Department of Pharmacy, Showa University Hospital, Tokyo, Japan. 2 Department of Hospital Pharmaceutics, School of Pharmacy, Showa University, Tokyo, Japan. 3 Department of Surgery, Division of General and Gastroenterological Surgery, School of Medicine, Showa University, Tokyo, Japan. 4 Showa University Esophageal … iowa ticket salesWebOct 25, 1997 · Cisplatin regimens can lead to a more or less pronounced hyponatremia in 4 to 10% of cases due to salt wasting with hypomagnesemia and normokaliemia. Functional and renal failure and orthostatic hypotension can be observed. Case report: Hyponatremia with confusion occurred after each cisplatin perfusion. iowa timberland values per acre